Repeated vaginal administration of trimeric HIV-1 clade C gp140 induces serum and mucosal antibody responses

Vaccine-mediated prevention of primary infection with human immunodeficiency virus (HIV) may require the sustained production of antibody at mucosal portals of entry. Here, we describe a novel approach of repeated mucosal immunization by delivering an HIV-1 envelope glycoprotein (gp) in a gel formul...

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Hlavní autoři: Cranage, MP, Fraser, CA, Stevens, Z, Huting, J, Chang, M, Jeffs, SA, Seaman, MS, Cope, A, Cole, T, Shattock, RJ
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761690/
https://ncbi.nlm.nih.gov/pubmed/19741600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2009.110
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