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Repeated vaginal administration of trimeric HIV-1 clade C gp140 induces serum and mucosal antibody responses
Vaccine-mediated prevention of primary infection with human immunodeficiency virus (HIV) may require the sustained production of antibody at mucosal portals of entry. Here, we describe a novel approach of repeated mucosal immunization by delivering an HIV-1 envelope glycoprotein (gp) in a gel formul...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761690/ https://ncbi.nlm.nih.gov/pubmed/19741600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2009.110 |
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