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Transferrin conjugation confers mucosal molecular targeting to a model HIV-1 trimeric gp140 vaccine antigen()

The generation of effective immune responses by mucosal vaccination without the use of inflammatory adjuvants, that compromise the epithelial barrier and recruit new cellular targets, is a key goal of vaccines designed to protect against sexually acquired pathogens. In the present study we use a mod...

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Detalhes bibliográficos
Main Authors: Mann, J.F.S., Stieh, D., Klein, K., de Stegmann, D.S. Miranda, Cranage, M.P., Shattock, R.J., McKay, P.F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314955/
https://ncbi.nlm.nih.gov/pubmed/22119743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.11.009
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