Mucosal Application of gp140 Encoding DNA Polyplexes to Different Tissues Results in Altered Immunological Outcomes in Mice

Increasing evidence suggests that mucosally targeted vaccines will enhance local humoral and cellular responses whilst still eliciting systemic immunity. We therefore investigated the capacity of nasal, sublingual or vaginal delivery of DNA-PEI polyplexes to prime immune responses prior to mucosal p...

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Bibliografski detalji
Glavni autori: Mann, Jamie F. S., McKay, Paul F., Arokiasamy, Samantha, Patel, Reeyeshkumar K., Tregoning, John S., Shattock, Robin J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691144/
https://ncbi.nlm.nih.gov/pubmed/23826293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067412
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