Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection()

Vaccination through mucosal surfaces has been shown to elicit antiviral immune responses against a number of mucosal pathogens. Here we demonstrate that both mucosal and systemic immune responses can be elicited against a model HIV-1 CN54gp140 antigen when cation-complexed plasmid DNA vaccines are a...

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Hlavní autoři: Mann, Jamie F.S., McKay, Paul F., Arokiasamy, Samantha, Patel, Reeyeshkumar K., Klein, Katja, Shattock, Robin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science Publishers 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767111/
https://ncbi.nlm.nih.gov/pubmed/23774102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.06.004
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