Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection()

Vaccination through mucosal surfaces has been shown to elicit antiviral immune responses against a number of mucosal pathogens. Here we demonstrate that both mucosal and systemic immune responses can be elicited against a model HIV-1 CN54gp140 antigen when cation-complexed plasmid DNA vaccines are a...

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Detalhes bibliográficos
Main Authors: Mann, Jamie F.S., McKay, Paul F., Arokiasamy, Samantha, Patel, Reeyeshkumar K., Klein, Katja, Shattock, Robin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767111/
https://ncbi.nlm.nih.gov/pubmed/23774102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.06.004
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