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Intravaginal immunisation using a novel antigen-releasing ring device elicits robust vaccine antigen-specific systemic and mucosal humoral immune responses
The generation of effective levels of antigen-specific immunity at the mucosal sites of pathogen entry is a key goal for vaccinologists. We explored topical vaginal application as an approach to initiate local antigen-specific immunity, enhance previously existing systemic immunity or re-target resp...
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Pubblicato in: | J Control Release |
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Autori principali: | , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Elsevier Science Publishers
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333785/ https://ncbi.nlm.nih.gov/pubmed/28115243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.01.018 |
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