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Chemokine-Adjuvanted Plasmid DNA Induces Homing of Antigen-Specific and Non–Antigen-Specific B and T Cells to the Intestinal and Genital Mucosae

Plasmid DNA is a promising vaccine platform that together with electroporation can elicit significant systemic Ab responses; however, immunity at mucosal sites remains low. In this study, we sought to program T and B cells to home to the gastrointestinal and vaginal mucosae using genetic chemokine a...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Aldon, Yoann, Kratochvil, Sven, Shattock, Robin J., McKay, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994839/
https://ncbi.nlm.nih.gov/pubmed/31915263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901184
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