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Evaluation of TLR Agonists as Potential Mucosal Adjuvants for HIV gp140 and Tetanus Toxoid in Mice

In the present study we investigate the impact of a range of TLR ligands and chitosan as potential adjuvants for different routes of mucosal immunisation (sublingual (SL), intranasal (IN), intravaginal (IVag) and a parenteral route (subcutaneous (SC)) in the murine model. We assess their ability to...

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Detalhes bibliográficos
Main Authors: Buffa, Viviana, Klein, Katja, Fischetti, Lucia, Shattock, Robin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521731/
https://ncbi.nlm.nih.gov/pubmed/23272062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050529
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