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A “Prime-Pull” Vaccine Strategy Has a Modest Effect on Local and Systemic Antibody Responses to HIV gp140 in Mice

One potential strategy for the prevention of HIV infection is to induce virus specific mucosal antibody that can act as an immune barrier to prevent transmission. The mucosal application of chemokines after immunisation, termed “prime-pull”, has been shown to recruit T cells to mucosal sites. We wis...

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Detalhes bibliográficos
Main Authors: Tregoning, John S., Buffa, Viviana, Oszmiana, Anna, Klein, Katja, Walters, Adam A., Shattock, Robin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834027/
https://ncbi.nlm.nih.gov/pubmed/24260419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080559
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