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Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
Aberrant promoter hypermethylation is frequently observed in cancer. The potential for this mechanism to contribute to tumor development depends on whether the genes affected are repressed because of their methylation. Many aberrantly methylated genes play important roles in development and are biva...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060255/ https://ncbi.nlm.nih.gov/pubmed/21368160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013224108 |
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