Targeting of Rac GTPases blocks the spread of intact human breast cancer

High expression of Rac small GTPases in invasive breast ductal carcinoma is associated with poor prognosis, but its therapeutic value in human cancers is not clear. The aim of the current study was to determine the response of human primary breast cancers to Rac-based drug treatments ex vivo. Three-...

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Bibliographic Details
Main Authors: Katz, Elad, Sims, Andrew H., Sproul, Duncan, Caldwell, Helen, Dixon, J. Michael, Meehan, Richard R., Harrison, David J.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442288/
https://ncbi.nlm.nih.gov/pubmed/22689141
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