Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

BACKGROUND: Aberrant CpG island promoter DNA hypermethylation is frequently observed in cancer and is believed to contribute to tumor progression by silencing the expression of tumor suppressor genes. Previously, we observed that promoter hypermethylation in breast cancer reflects cell lineage rathe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sproul, Duncan, Kitchen, Robert R, Nestor, Colm E, Dixon, J Michael, Sims, Andrew H, Harrison, David J, Ramsahoye, Bernard H, Meehan, Richard R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2012
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491412/
https://ncbi.nlm.nih.gov/pubmed/23034185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-10-r84
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