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Distinct Ligand Specificity of the Tiam1 and Tiam2 PDZ Domains
Guanine nucleotide exchange factor proteins of the Tiam family are activators of the Rho GTPase Rac1 and critical for cell morphology, adhesion, migration, and polarity. These proteins are modular and contain a variety of interaction domains, including a single post-synaptic density-95/discs large/z...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059893/ https://ncbi.nlm.nih.gov/pubmed/21192692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1013613 |
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