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Distinct Ligand Specificity of the Tiam1 and Tiam2 PDZ Domains

Guanine nucleotide exchange factor proteins of the Tiam family are activators of the Rho GTPase Rac1 and critical for cell morphology, adhesion, migration, and polarity. These proteins are modular and contain a variety of interaction domains, including a single post-synaptic density-95/discs large/z...

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Sonraí Bibleagrafaíochta
Main Authors: Shepherd, Tyson R., Hard, Ryan L., Murray, Ann M., Pei, Dehua, Fuentes, Ernesto J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059893/
https://ncbi.nlm.nih.gov/pubmed/21192692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1013613
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