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Simultaneous Binding of Two Peptidyl Ligands by a Src Homology 2 Domain
Src homology 2 (SH2) domains mediate protein-protein interactions by recognizing phosphotyrosine (pY)-containing sequences of target proteins. In all of the SH2 domain-pY peptide interactions described to date, the SH2 domain binds to a single pY peptide. Here, determination of the co-crystal struct...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164524/ https://ncbi.nlm.nih.gov/pubmed/21800896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200439v |
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