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Evidence for a High Spin Fe(IV) Species in the Catalytic Cycle of a Bacterial Phenylalanine Hydroxylase

Phenylalanine hydroxylase is a mononuclear non-heme iron protein that uses tetrahydropterin as the source of the two electrons needed to activate dioxygen for the hydroxylation of phenylalanine to tyrosine. Rapid-quench methods have been used to analyze the mechanism of a bacterial phenylalanine hyd...

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Detalhes bibliográficos
Main Authors: Panay, Aram Joel, Lee, Michael, Krebs, Carsten, Bollinger, J. Martin, Fitzpatrick, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059337/
https://ncbi.nlm.nih.gov/pubmed/21261288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1019868
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