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Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region
The five genes of the human growth hormone (hGH) cluster are expressed in either the pituitary or placenta. Activation of the cluster is dependent on a locus control region (LCR) comprising pituitary- specific (HSI,II, –15 kb), placenta-specific (HSIV, –30 kb) and shared (HSIII, –28 kb; HSV, –32 kb)...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305892/ https://ncbi.nlm.nih.gov/pubmed/11118216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.24.6814 |
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