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Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region

The five genes of the human growth hormone (hGH) cluster are expressed in either the pituitary or placenta. Activation of the cluster is dependent on a locus control region (LCR) comprising pituitary- specific (HSI,II, –15 kb), placenta-specific (HSIV, –30 kb) and shared (HSIII, –28 kb; HSV, –32 kb)...

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Bibliographische Detailangaben
Hauptverfasser: Elefant, Felice, Su, Yuhua, Liebhaber, Stephen A., Cooke, Nancy E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC305892/
https://ncbi.nlm.nih.gov/pubmed/11118216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.24.6814
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