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An Autoregulatory Pathway Establishes the Definitive Chromatin Conformation at the Pit-1 Locus
The transcription factor Pit-1 (POU1-F1) plays a dominant role in cell lineage expansion and differentiation in the anterior pituitary. Prior studies of the mouse Pit-1 (mPit-1) gene revealed that this master regulatory locus is activated at embryonic day 13.5 (E13.5) by an early enhancer (EE), wher...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387207/ https://ncbi.nlm.nih.gov/pubmed/25691665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01283-14 |
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