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The Role of the hGH Locus Control Region in Somatotrope Restriction of hGH-N Gene Expression

Expression of mammalian GH is normally restricted to somatotropes and somatolactotropes (somatotrope lineages) in the anterior pituitary. The basis for this restriction remains incompletely understood. Recent studies indicate that deoxyribonuclease I hypersensitive site I (HSI) of the hGH locus cont...

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Détails bibliographiques
Auteurs principaux: Ho, Yugong, Liebhaber, Stephen A., Cooke, Nancy E.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082332/
https://ncbi.nlm.nih.gov/pubmed/21415161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0411
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