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The Role of the hGH Locus Control Region in Somatotrope Restriction of hGH-N Gene Expression

Expression of mammalian GH is normally restricted to somatotropes and somatolactotropes (somatotrope lineages) in the anterior pituitary. The basis for this restriction remains incompletely understood. Recent studies indicate that deoxyribonuclease I hypersensitive site I (HSI) of the hGH locus cont...

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Detalhes bibliográficos
Main Authors: Ho, Yugong, Liebhaber, Stephen A., Cooke, Nancy E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082332/
https://ncbi.nlm.nih.gov/pubmed/21415161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0411
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