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The Role of the hGH Locus Control Region in Somatotrope Restriction of hGH-N Gene Expression

Expression of mammalian GH is normally restricted to somatotropes and somatolactotropes (somatotrope lineages) in the anterior pituitary. The basis for this restriction remains incompletely understood. Recent studies indicate that deoxyribonuclease I hypersensitive site I (HSI) of the hGH locus cont...

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Main Authors: Ho, Yugong, Liebhaber, Stephen A., Cooke, Nancy E.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082332/
https://ncbi.nlm.nih.gov/pubmed/21415161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0411
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