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The Role of the hGH Locus Control Region in Somatotrope Restriction of hGH-N Gene Expression

Expression of mammalian GH is normally restricted to somatotropes and somatolactotropes (somatotrope lineages) in the anterior pituitary. The basis for this restriction remains incompletely understood. Recent studies indicate that deoxyribonuclease I hypersensitive site I (HSI) of the hGH locus cont...

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Autores principales: Ho, Yugong, Liebhaber, Stephen A., Cooke, Nancy E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082332/
https://ncbi.nlm.nih.gov/pubmed/21415161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0411
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