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The juxtaposition of a promoter with a locus control region transcriptional domain activates gene expression
Nonlinear chromatin configurations can juxtapose widely separated elements within a genomic locus; however, it remains unclear how these structures are established and contribute to transcriptional control. A 5′-remote locus control region (LCR) regulates the human growth hormone (hGH-N) gene. HSI,...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529346/ https://ncbi.nlm.nih.gov/pubmed/18636089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.126 |
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