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KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

Mutations in HERG and KCNQ1 (or KVLQT1) genes cause the life-threatening Long QT syndrome. These genes encode K(+) channel pore-forming subunits that associate with ancillary subunits from the KCNE family to underlie the two components, I(Kr) and I(Ks), of the human cardiac delayed rectifier current...

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Udgivet i:EMBO J
Principais autores: Tinel, Norbert, Diochot, Sylvie, Borsotto, Marc, Lazdunski, Michel, Barhanin, Jacques
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11101505/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.23.6326
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