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Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K(+) channels

Group I metabotropic glutamate receptors (mGluRs) are implicated in diverse processes such as learning, memory, epilepsy, pain and neuronal death. By inhibiting background K(+) channels, group I mGluRs mediate slow and long-lasting excitation. The main neuronal representatives of this K(+) channel f...

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Bibliographic Details
Published in:EMBO J
Main Authors: Chemin, Jean, Girard, Christophe, Duprat, Fabrice, Lesage, Florian, Romey, Georges, Lazdunski, Michel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14532113/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg528
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