Targeting of human interleukin-12B by small hairpin RNAs in xenografted psoriatic skin

BACKGROUND: Psoriasis is a chronic inflammatory skin disorder that shows as erythematous and scaly lesions. The pathogenesis of psoriasis is driven by a dysregulation of the immune system which leads to an altered cytokine production. Proinflammatory cytokines that are up-regulated in psoriasis incl...

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Detalhes bibliográficos
Main Authors: Bak, Rasmus O, Stenderup, Karin, Rosada, Cecilia, Petersen, Line B, Moldt, Brian, Dagnæs-Hansen, Frederik, Jakobsen, Maria, Kamp, Søren, Jensen, Thomas G, Dam, Tomas N, Mikkelsen, Jacob Giehm
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058081/
https://ncbi.nlm.nih.gov/pubmed/21352568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-5945-11-5
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