Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model

Tumor necrosis factor-α (TNF-α) is upregulated in psoriatic skin and represents a prominent target in psoriasis treatment. The level of TNF-α-encoding mRNA, however, is not increased in psoriatic skin, and it remains unclear whether intervention strategies based on RNA interference (RNAi) are therap...

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Detalhes bibliográficos
Main Authors: Jakobsen, Maria, Stenderup, Karin, Rosada, Cecilia, Moldt, Brian, Kamp, Søren, Dam, Tomas N, Jensen, Thomas G, Mikkelsen, Jacob Giehm
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835022/
https://ncbi.nlm.nih.gov/pubmed/19568223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.141
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