Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells

Preferential repair of bulky DNA adducts from the transcribed genes via nucleotide excision repair is well characterized in mammalian cells. However, definitive evidence is lacking for similar repair of oxidized bases, the major endogenous DNA lesions. Here we show that the oxidized base-specific hu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Banerjee, Dibyendu, Mandal, Santi M., Das, Aditi, Hegde, Muralidhar L., Das, Soumita, Bhakat, Kishor K., Boldogh, Istvan, Sarkar, Partha S., Mitra, Sankar, Hazra, Tapas K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
DNA and Chromosomes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057786/
https://ncbi.nlm.nih.gov/pubmed/21169365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198796
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