Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells

Preferential repair of bulky DNA adducts from the transcribed genes via nucleotide excision repair is well characterized in mammalian cells. However, definitive evidence is lacking for similar repair of oxidized bases, the major endogenous DNA lesions. Here we show that the oxidized base-specific hu...

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Bibliographic Details
Main Authors: Banerjee, Dibyendu, Mandal, Santi M., Das, Aditi, Hegde, Muralidhar L., Das, Soumita, Bhakat, Kishor K., Boldogh, Istvan, Sarkar, Partha S., Mitra, Sankar, Hazra, Tapas K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
DNA and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057786/
https://ncbi.nlm.nih.gov/pubmed/21169365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198796
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