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Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells
Preferential repair of bulky DNA adducts from the transcribed genes via nucleotide excision repair is well characterized in mammalian cells. However, definitive evidence is lacking for similar repair of oxidized bases, the major endogenous DNA lesions. Here we show that the oxidized base-specific hu...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057786/ https://ncbi.nlm.nih.gov/pubmed/21169365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198796 |
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