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Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells

Preferential repair of bulky DNA adducts from the transcribed genes via nucleotide excision repair is well characterized in mammalian cells. However, definitive evidence is lacking for similar repair of oxidized bases, the major endogenous DNA lesions. Here we show that the oxidized base-specific hu...

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Detalhes bibliográficos
Main Authors: Banerjee, Dibyendu, Mandal, Santi M., Das, Aditi, Hegde, Muralidhar L., Das, Soumita, Bhakat, Kishor K., Boldogh, Istvan, Sarkar, Partha S., Mitra, Sankar, Hazra, Tapas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057786/
https://ncbi.nlm.nih.gov/pubmed/21169365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198796
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