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Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein

Recent studies demonstrate a pivotal role for bone morphogenic protein-6 (BMP6) and matriptase-2, a protein encoded by the TMPRSS6 gene, in the induction and suppression of hepatic hepcidin expression, respectively. We examined their expression profiles in the liver and showed a predominant localiza...

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Bibliografiske detaljer
Main Authors: Zhang, An-Sheng, Anderson, Sheila A., Wang, Jiaohong, Yang, Fan, DeMaster, Kristina, Ahmed, Riffat, Nizzi, Christopher P., Eisenstein, Richard S., Tsukamoto, Hidekazu, Enns, Caroline A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056593/
https://ncbi.nlm.nih.gov/pubmed/21115976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-287292
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