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Low Intracellular Iron Increases the Stability of Matriptase-2
Matriptase-2 (MT2) is a type II transmembrane serine protease that is predominantly expressed in hepatocytes. It suppresses the expression of hepatic hepcidin, an iron regulatory hormone, by cleaving membrane hemojuvelin into an inactive form. Hemojuvelin is a bone morphogenetic protein (BMP) co-rec...
Tallennettuna:
| Julkaisussa: | J Biol Chem |
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| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326848/ https://ncbi.nlm.nih.gov/pubmed/25550162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611913 |
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