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The Apolipoprotein E Antagonistic Pleiotropy Hypothesis: Review and Recommendations

Research on apolipoprotein E (APOE) has consistently revealed a relationship between the gene's ε4 allele and risk for development of Alzheimer's disease (AD). However, research with younger populations of ε4 carriers has suggested that the APOE ε4 allele may in fact be beneficial in earli...

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Bibliografiske detaljer
Main Authors: Tuminello, Elizabeth R., Han, S. Duke
Format: Artigo
Sprog:Inglês
Udgivet: SAGE-Hindawi Access to Research 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056453/
https://ncbi.nlm.nih.gov/pubmed/21423560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/726197
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