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Is antagonistic pleiotropy ubiquitous in aging biology?

Lay Summary: An evolutionary mechanism of aging was hypothesized 60 years ago to be the genetic trade-off between early life fitness and late life mortality. Genetic evidence supporting this hypothesis was unavailable then, but has accumulated recently. These tradeoffs, known as antagonistic pleiotr...

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Vydáno v:Evol Med Public Health
Hlavní autoři: Austad, Steven N, Hoffman, Jessica M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276058/
https://ncbi.nlm.nih.gov/pubmed/30524730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eoy033
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