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The Apolipoprotein E Antagonistic Pleiotropy Hypothesis: Review and Recommendations

Research on apolipoprotein E (APOE) has consistently revealed a relationship between the gene's ε4 allele and risk for development of Alzheimer's disease (AD). However, research with younger populations of ε4 carriers has suggested that the APOE ε4 allele may in fact be beneficial in earli...

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Détails bibliographiques
Auteurs principaux: Tuminello, Elizabeth R., Han, S. Duke
Format: Artigo
Langue:Inglês
Publié: SAGE-Hindawi Access to Research 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056453/
https://ncbi.nlm.nih.gov/pubmed/21423560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/726197
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