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The Apolipoprotein E Antagonistic Pleiotropy Hypothesis: Review and Recommendations

Research on apolipoprotein E (APOE) has consistently revealed a relationship between the gene's ε4 allele and risk for development of Alzheimer's disease (AD). However, research with younger populations of ε4 carriers has suggested that the APOE ε4 allele may in fact be beneficial in earli...

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Detalhes bibliográficos
Main Authors: Tuminello, Elizabeth R., Han, S. Duke
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056453/
https://ncbi.nlm.nih.gov/pubmed/21423560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/726197
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