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The Apolipoprotein E Antagonistic Pleiotropy Hypothesis: Review and Recommendations

Research on apolipoprotein E (APOE) has consistently revealed a relationship between the gene's ε4 allele and risk for development of Alzheimer's disease (AD). However, research with younger populations of ε4 carriers has suggested that the APOE ε4 allele may in fact be beneficial in earli...

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Hlavní autoři: Tuminello, Elizabeth R., Han, S. Duke
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE-Hindawi Access to Research 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056453/
https://ncbi.nlm.nih.gov/pubmed/21423560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/726197
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