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Apolipoprotein E (ApoE) polymorphism is related to differences in potential fertility in women: a case of antagonistic pleiotropy?

The alleles that are detrimental to health, especially in older age, are thought to persist in populations because they also confer some benefits for individuals (through antagonistic pleiotropy). The ApoE4 allele at the ApoE locus, encoding apolipoprotein E (ApoE), significantly increases risk of p...

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Detalles Bibliográficos
Publicado en:Proc Biol Sci
Main Authors: Jasienska, Grazyna, Ellison, Peter T., Galbarczyk, Andrzej, Jasienski, Michal, Kalemba-Drozdz, Malgorzata, Kapiszewska, Maria, Nenko, Ilona, Thune, Inger, Ziomkiewicz, Anna
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345437/
https://ncbi.nlm.nih.gov/pubmed/25673673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2014.2395
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