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Apolipoprotein E (ApoE) polymorphism is related to differences in potential fertility in women: a case of antagonistic pleiotropy?

The alleles that are detrimental to health, especially in older age, are thought to persist in populations because they also confer some benefits for individuals (through antagonistic pleiotropy). The ApoE4 allele at the ApoE locus, encoding apolipoprotein E (ApoE), significantly increases risk of p...

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Dades bibliogràfiques
Publicat a:Proc Biol Sci
Autors principals: Jasienska, Grazyna, Ellison, Peter T., Galbarczyk, Andrzej, Jasienski, Michal, Kalemba-Drozdz, Malgorzata, Kapiszewska, Maria, Nenko, Ilona, Thune, Inger, Ziomkiewicz, Anna
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345437/
https://ncbi.nlm.nih.gov/pubmed/25673673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2014.2395
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