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Transcription-dependent R-loop formation at mammalian class switch sequences

Immunoglobulin class switching is mediated by recombination between switch sequences located immediately upstream of the immunoglobulin constant heavy chain genes. Targeting of recombination to particular switch sequences is associated temporally with transcription through these regions. We recently...

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Detalhes bibliográficos
Main Authors: Tracy, Robert B., Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305644/
https://ncbi.nlm.nih.gov/pubmed/10698946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.5.1055
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