Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

Pericytes play a key role in the development of cerebral microcirculation. The exact role of pericytes in the neurovascular unit in the adult brain and during brain aging remains, however, elusive. Using adult viable pericyte-deficient mice, we show that pericyte loss leads to brain vascular damage...

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Hauptverfasser: Bell, Robert D., Winkler, Ethan A., Sagare, Abhay P., Singh, Itender, LaRue, Barb, Deane, Rashid, Zlokovic, Berislav V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056408/
https://ncbi.nlm.nih.gov/pubmed/21040844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.09.043
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