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Endothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrier
Activated protein C (APC), a serine-protease with anticoagulant, anti-inflammatory, and cytoprotective activities, is neuroprotective and holds potential to treat different neurological disorders. It is unknown whether APC crosses the blood-brain barrier (BBB) to reach its therapeutic targets in the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895315/ https://ncbi.nlm.nih.gov/pubmed/18841163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.117 |
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