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Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

Pericytes play a key role in the development of cerebral microcirculation. The exact role of pericytes in the neurovascular unit in the adult brain and during brain aging remains, however, elusive. Using adult viable pericyte-deficient mice, we show that pericyte loss leads to brain vascular damage...

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Main Authors: Bell, Robert D., Winkler, Ethan A., Sagare, Abhay P., Singh, Itender, LaRue, Barb, Deane, Rashid, Zlokovic, Berislav V.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056408/
https://ncbi.nlm.nih.gov/pubmed/21040844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.09.043
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