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Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles
Mutations in CAPN3/Capn3, which codes for skeletal muscle-specific calpain-3/p94 protease, are responsible for limb-girdle muscular dystrophy type 2A (LGMD2A). Using “knock-in” (referred to as Capn3(CS/CS)) mice, in which the endogenous calpain-3 is replaced with a mutant calpain-3:C129S, that is pr...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056149/ https://ncbi.nlm.nih.gov/pubmed/21295580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.01.057 |
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