Skeletal Muscle-specific Calpain Is an Intracellular Na(+)-dependent Protease

Because intracellular [Na(+)] is kept low by Na(+)/K(+)-ATPase, Na(+) dependence is generally considered a property of extracellular enzymes. However, we found that p94/calpain 3, a skeletal-muscle-specific member of the Ca(2+)-activated intracellular “modulator proteases” that is responsible for a...

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Detalles Bibliográficos
Main Authors: Ono, Yasuko, Ojima, Koichi, Torii, Fukuyo, Takaya, Emi, Doi, Naoko, Nakagawa, Kazuhiro, Hata, Shoji, Abe, Keiko, Sorimachi, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Enzymology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906292/
https://ncbi.nlm.nih.gov/pubmed/20460380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126946
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