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Methotrexate supports in vivo selection of human embryonic stem cell derived-hematopoietic cells expressing dihydrofolate reductase

Human embryonic stem cells (hES Cs) are an attractive alternative cell source for hematopoietic gene therapy applications as the cells are easily modified with lentiviral or other vectors and can be subsequently induced to differentiate into hematopoietic progenitor cells. However, demonstration of...

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Bibliografski detalji
Glavni autori: Gori, Jennifer L, McIvor, R Scott, Kaufman, Dan S
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056096/
https://ncbi.nlm.nih.gov/pubmed/21468213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.6.12390
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