In vivo protection of activated Tyr22-dihydrofolate reductase gene-modified canine T lymphocytes from methotrexate

BACKGROUND: Nonmyeloablative allogeneic hematopoietic stem cell (HSC) transplantation can cure malignant and nonmalignant diseases affecting the hematopoietic system, such as severe combined immunodeficiencies, aplastic anemia and hemoglobinopathies. Although nonmyeloablative is favored over myeloab...

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Autores principales: Gori, Jennifer L., Beard, Brian C., Williams, Nathaniel P., Ironside, Christina, Swanson, Debra, McIvor, R. Scott, Kiem, HP
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886817/
https://ncbi.nlm.nih.gov/pubmed/23666780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2713
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