In vivo protection of activated Tyr22-dihydrofolate reductase gene-modified canine T lymphocytes from methotrexate

BACKGROUND: Nonmyeloablative allogeneic hematopoietic stem cell (HSC) transplantation can cure malignant and nonmalignant diseases affecting the hematopoietic system, such as severe combined immunodeficiencies, aplastic anemia and hemoglobinopathies. Although nonmyeloablative is favored over myeloab...

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Hlavní autoři: Gori, Jennifer L., Beard, Brian C., Williams, Nathaniel P., Ironside, Christina, Swanson, Debra, McIvor, R. Scott, Kiem, HP
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886817/
https://ncbi.nlm.nih.gov/pubmed/23666780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2713
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