In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase

Human embryonic stem cells (hESCs) provide a novel source of hematopoietic and other cell populations suitable for gene therapy applications. Preclinical studies to evaluate engraftment of hESC-derived hematopoietic cells transplanted into immunodeficient mice demonstrate only limited repopulation....

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Hlavní autoři: Gori, Jennifer L., Tian, Xinghui, Swanson, Debra, Gunther, Roland, Shultz, Leonard D., McIvor, R. Scott, Kaufman, Dan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820606/
https://ncbi.nlm.nih.gov/pubmed/19829316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.131
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