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Transcription factor Sp3 is essential for post-natal survival and late tooth development

Sp3 is a ubiquitously expressed transcription factor closely related to Sp1 (specificity protein 1). We have disrupted the mouse Sp3 gene by homologous recombination. Sp3-deficient embryos are growth retarded and invariably die at birth of respiratory failure. The cause for the observed breathing de...

詳細記述

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書誌詳細
主要な著者: Bouwman, Peter, Göllner, Heike, Elsässer, Hans-Peter, Eckhoff, Gabriele, Karis, Alar, Grosveld, Frank, Philipsen, Sjaak, Suske, Guntram
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC305603/
https://ncbi.nlm.nih.gov/pubmed/10675334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.655
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