Specificity Protein 2 (Sp2) Is Essential for Mouse Development and Autonomous Proliferation of Mouse Embryonic Fibroblasts

BACKGROUND: The zinc finger protein Sp2 (specificity protein 2) is a member of the glutamine-rich Sp family of transcription factors. Despite its close similarity to Sp1, Sp3 and Sp4, Sp2 does not bind to DNA or activate transcription when expressed in mammalian cell lines. The expression pattern an...

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Detalhes bibliográficos
Main Authors: Baur, Frank, Nau, Kerstin, Sadic, Dennis, Allweiss, Lena, Elsässer, Hans-Peter, Gillemans, Nynke, de Wit, Ton, Krüger, Imme, Vollmer, Marion, Philipsen, Sjaak, Suske, Guntram
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833205/
https://ncbi.nlm.nih.gov/pubmed/20221402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009587
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