Epigenetic Silencing of Spermatocyte-Specific and Neuronal Genes by SUMO Modification of the Transcription Factor Sp3

SUMO modification of transcription factors is linked to repression of transcription. The physiological significance of SUMO attachment to a particular transcriptional regulator, however, is largely unknown. We have employed the ubiquitously expressed murine transcription factor Sp3 to analyze the ro...

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Détails bibliographiques
Auteurs principaux: Stielow, Bastian, Krüger, Imme, Diezko, Rolf, Finkernagel, Florian, Gillemans, Nynke, Kong-a-San, John, Philipsen, Sjaak, Suske, Guntram
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978682/
https://ncbi.nlm.nih.gov/pubmed/21085687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001203
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