Transcription factor Sp3 is silenced through SUMO modification by PIAS1

Sp3 is a ubiquitous transcription factor closely related to Sp1. Here we show that Sp3 is a target for SUMO modification in vivo and in vitro. SUMO modification of Sp3 occurs at a single lysine located between the second glutamine-rich activation domain and the DNA-binding domain. Mutational analyse...

Full description

Saved in:
Bibliographic Details
Main Authors: Sapetschnig, Alexandra, Rischitor, Grigore, Braun, Harald, Doll, Andreas, Schergaut, Marion, Melchior, Frauke, Suske, Guntram
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC129032/
https://ncbi.nlm.nih.gov/pubmed/12356736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf510
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items