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Transcription factor Sp3 is silenced through SUMO modification by PIAS1
Sp3 is a ubiquitous transcription factor closely related to Sp1. Here we show that Sp3 is a target for SUMO modification in vivo and in vitro. SUMO modification of Sp3 occurs at a single lysine located between the second glutamine-rich activation domain and the DNA-binding domain. Mutational analyse...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129032/ https://ncbi.nlm.nih.gov/pubmed/12356736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf510 |
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