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The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties
Targeted disruption of both alleles of mouse sos1, which encodes a Ras-specific exchange factor, conferred mid-gestational embryonic lethality that was secondary to impaired placental development and was associated with very low placental ERK activity. The trophoblastic layers of sos1(–/–) embryos w...
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| 出版年: | EMBO J |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.642 |
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