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The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties
Targeted disruption of both alleles of mouse sos1, which encodes a Ras-specific exchange factor, conferred mid-gestational embryonic lethality that was secondary to impaired placental development and was associated with very low placental ERK activity. The trophoblastic layers of sos1(–/–) embryos w...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305602/ https://ncbi.nlm.nih.gov/pubmed/10675333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.642 |
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