The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.

We have compared aspects of the mouse sos1 (msos1) and msos2 genes, which encode widely expressed, closely related Ras-specific exchange factors. Although an msos1 plasmid did not induce phenotypic changes in NIH 3T3 cells, addition of a 15-codon myristoylation signal to its 5' end enabled the resul...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Nielsen, K H, Papageorge, A G, Vass, W C, Willumsen, B M, Lowy, D R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232570/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.7132
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