The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties
Targeted disruption of both alleles of mouse sos1, which encodes a Ras-specific exchange factor, conferred mid-gestational embryonic lethality that was secondary to impaired placental development and was associated with very low placental ERK activity. The trophoblastic layers of sos1(–/–) embryos w...
Zapisane w:
| Wydane w: | EMBO J |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2000
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.642 |
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